GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs9309473 | 1 | rs7594511 | chr2:73681639 | ALMS1P | chr2:73872046-73912692:+ | 0.35 | 5.17 | 3.85E-7 | Metabolite levels |
| BLCA | cis | rs60843830 | 1 | rs7595075 | chr2:264019 | SH3YL1 | chr2:218138-264810:- | -0.45 | -11.68 | 3.7E-27 | Spherical equivalent (joint main effects and education interaction) |
| BLCA | cis | rs9309473 | 1 | rs7598396 | chr2:73652628 | ALMS1P | chr2:73872046-73912692:+ | 0.36 | 5.33 | 1.68E-7 | Metabolite levels |
| BLCA | cis | rs9309473 | 1 | rs7598419 | chr2:73798223 | ALMS1P | chr2:73872046-73912692:+ | 0.32 | 4.7 | 3.68E-6 | Metabolite levels |
| BLCA | cis | rs4372836 | 1 | rs7598876 | chr2:28974466 | TRMT61B | chr2:29072690-29093175:- | -0.29 | -5.13 | 4.54E-7 | Body mass index |
| BLCA | cis | rs7789940 | 1 | rs76024966 | chr7:75995021 | UPK3B | chr7:76139745-76157197:+ | -0.32 | -6.51 | 2.36E-10 | Multiple sclerosis |
| BLCA | cis | rs9309473 | 1 | rs7604682 | chr2:73788026 | ALMS1P | chr2:73872046-73912692:+ | 0.39 | 5.8 | 1.43E-8 | Metabolite levels |
| BLCA | cis | rs6547741 | 1 | rs7604798 | chr2:27824940 | C2orf16 | chr2:27799389-27805588:+ | 0.23 | 4.03 | 6.8E-5 | Oral cavity cancer |
| BLCA | cis | rs1930961 | 1 | rs760555 | chr22:25872837 | CRYBB2 | chr22:25615612-25627836:+ | 0.93 | 9.62 | 9.23E-20 | Bipolar disorder with mood-incongruent psychosis |
| BLCA | cis | rs60843830 | 1 | rs7605824 | chr2:280819 | SH3YL1 | chr2:218138-264810:- | 0.46 | 12.14 | 6.28E-29 | Spherical equivalent (joint main effects and education interaction) |
| BLCA | cis | rs9309473 | 1 | rs7607014 | chr2:73730174 | ALMS1P | chr2:73872046-73912692:+ | -0.34 | -5.05 | 6.84E-7 | Metabolite levels |
| BLCA | cis | rs344081 | 1 | rs7609851 | chr3:156638503 | LEKR1 | chr3:156544076-156763918:+ | -0.44 | -6.19 | 1.52E-9 | Bone mineral density |
| BLCA | cis | rs7611238 | 1 | rs7611238 | chr3:195072918 | C3orf21 | chr3:194789015-194991895:- | 0.27 | 5.52 | 6.34E-8 | Body mass index |
| BLCA | cis | rs10935120 | 1 | rs7611611 | chr3:134307877 | ANAPC13 | chr3:134196547-134204865:- | 0.48 | 7.6 | 2.33E-13 | Height |
| BLCA | cis | rs10935120 | 1 | rs7611828 | chr3:134250325 | ANAPC13 | chr3:134196547-134204865:- | 0.49 | 7.7 | 1.15E-13 | Height |